| Popis: |
The researchers are working hard to discover eco-friendly alternatives to chemically synthesized metal nanoparticles. The current study used Corchorus aestuans to evaluate bio-synthesis, physiochemical characterization and antimicrobial activities against human pathogenic bacteria and also the anti-cancer activity. The bio-synthesized Corchorus aestuans silver nanoparticles (CA-AgNPs) were characterized by UV, FT-IR, powder XRD, FE-SEM, EDAX, HR-TEM, DLS and Zeta potential. UV- Visible spectrum of the aqueous solution showed a peak at 426 nm confirming the presence of silver nanoparticles. FT-IR spectrum analysis shows the presence of functional groups. XRD spectrum shows that the bio-synthesized CA-AgNPs were crystalline in nature with a face-centered cubic structure (FCC). The TEM studies revealed that the size of the synthesized CA-AgNPs was about 13 nm. The zeta potential value of -17.9 mV exhibits those bio-synthesized nanoparticles has the excellent stability. The MTT assay also demonstrated improved cytotoxicity against bosom malignant breast cancer (MCF-7) cell lines with IC50 value of 56.47 µg/mL. The CA-AgNPs were also found to be anti-microbial effective against gram-positive and gram-negative bacteria and fungi. Furthermore, after 48 h of interaction, the bio-synthesized CA-AgNPs successfully degraded the Methylene blue (MB) dye nearly 91.19%. |
