Sudden death from ischaemic heart disease in a female patient with Sjögren syndrome
| Autor: | Masakazu Hanagama, Masayuki Nata, Hiromasa Inoue, Koji Kinoshita, Masanori Funauchi, Masafumi Sugiyama |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
medicine.medical_specialty
Sinoatrial node business.industry Health Policy Arteriolosclerosis Autopsy Arteriosclerosis medicine.disease Atrioventricular node Sudden death stomatognathic diseases Issues ethics and legal aspects medicine.anatomical_structure Internal medicine medicine Cardiology Electrical conduction system of the heart business Law Cause of death |
| Zdroj: | Medicine, Science and the Law. 48:261-265 |
| ISSN: | 2042-1818 0025-8024 |
| DOI: | 10.1258/rsmmsl.48.3.261 |
| Popis: | Primary Sjögren syndrome (SjS) has a comparatively good prognosis except when it is complicated by non-Hodgkin's lymphoma. We performed an autopsy on a young female patient with primary SjS who had died suddenly during a meal, and we discuss the relationship between primary SjS and the cause of death. Eosinophilic change of the cardiomyocytes and severe arteriolosclerosis were observed within the myocardium. In the conduction system, lymphocyte infiltration was detected in the bundle of His, in addition to arteriosclerosis in the sinoatrial node and atrioventricular node arteries. The cause of death was diagnosed as ischaemic heart disease induced by arteriolosclerosis: its development can probably be attributed mostly to primary SjS. It should thus be kept in mind that primary SjS can occasionally result in the development of cardiovascular complications, such as ischaemic heart disease, as well as systemic lupus erythematosus or rheumatoid arthritis. |
| Databáze: | OpenAIRE |
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