Abstract 8925: Current Clinical AF Treatment Targets Do Not Reflect Patient Priorities
| Autor: | Brian Zenger, Yue Zhang, Morgan Millar, T. J Bunch, Jonathan P Piccini, Rachel Hess, Benjamin A Steinberg |
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| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Circulation. 144 |
| ISSN: | 1524-4539 0009-7322 |
| Popis: | Background: AF clinical trials define success as freedom from any AF episode >30 seconds. Clinically AF treatment is geared towards managing patient symptoms, yet little is known about patients’ expectations for successful AF treatment. Objective: Determine patient expectations for successful AF treatment. Methods: Patients with an AF diagnosis from a tertiary electrophysiology clinic were asked to complete the Toronto Atrial Fibrillation Severity Scale (AFSS) from the perspective of current symptoms, worst ever symptoms, and expected symptoms after successful treatment. Survey and patient clinical data were linked through the EMR. Results: Of the survey respondents (n=27), 41% were female, mean age was 69 (SD 9.7 years), and 30% had prior ablation. Overall, 59% of these patients considered AF treatment successful even with AF occurring one per year or more, and 70% would still consider treatment successful with episodes lasting minutes or more. When selecting the most important factor of success, 80% of patients selected decrease in AF frequency, 20% selected decrease in severity of symptoms, and 0 selected decrease in episode duration. A minority of patients (19%) considered treatment successful only if they never had AF again. Conclusion: A small minority of patients with AF would consider their treatment successful if they never experienced an AF episode again, which contradicts our current assessment of AF treatments. If confirmed in larger cohorts, these data support redesigning AF clinical studies to match outcomes prioritized by patients. |
| Databáze: | OpenAIRE |
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