| Popis: |
1a mechanical method of artificially detaching the retina was considered. The startling fact that spontaneous reattachment occurred regardless of the hole in the retina after a period of six weeks led us to try other methods. It has been known for a long time that detached retina occurs often in a soft eye. Also, in those highly myopic eyes which seem more predisposed to this condition, the existence of what is called "fluid vitreous" has always been a questionable quantity. Redslob and Reiss 2 demonstrated conclusively that changes in the ph of intra-ocular fluids play an important and direct r\l=o^\lein the maintenance of the intra-ocular tension. If the ph is on the acid side, the tension tends to be lowered, while the alkaline ion raises this factor. We tried various dilutions of acetic and hydrochloric acids, and while we were able to produce a detachment by this method, we found it beyond control. An acid strong enough to cause the detachment went further and disintegrated the retina and choroid. If the acid was not of a certain maximal strength, no detachment occurred. Finally, trypsin was tried. In stock concentrations, digestion took place after detachment. However, by diluting the trypsin a detachment occurred without destruction of the layers and remained over a long period of time. We were greatly interested to know just what changes in the make-up of the vitreous took place. The table shows a comparison of the various elements of the vitreous in the normal rabbit's vitreous, and in vitreous treated with trypsin. The figures represent the average findings of several analyses which checked very closely. This portion of the work was done by Mr. Irving Puntenney, a medical student specializing in chemistry, with the cooperation of Dr. C. O. Miller of the chemistry |
