Pharmacokinetics and concentration-effect relationship of adalimumab in rheumatoid arthritis
| Autor: | Hervé Watier, Gilles Paintaud, Piéra Fuzibet, Olivier Vittecoq, Emilie Ducourau, Céline Vignault, Thierry Lequerré, Xavier Le Loët, Philippe Goupille, Denis Mulleman, David Ternant |
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| Rok vydání: | 2015 |
| Předmět: |
musculoskeletal diseases
Pharmacology biology business.industry C-reactive protein medicine.disease humanities Antirheumatic Agents Pharmacokinetics Pharmacodynamics Rheumatoid arthritis biology.protein Adalimumab Medicine Pharmacology (medical) Young adult skin and connective tissue diseases Prospective cohort study business medicine.drug |
| Zdroj: | British Journal of Clinical Pharmacology. 79:286-297 |
| ISSN: | 0306-5251 |
| DOI: | 10.1111/bcp.12509 |
| Popis: | Aims This study aimed at describing adalimumab pharmacokinetics (PK) and the concentration–effect relationship of adalimumab using pharmacokinetic–pharmacodynamic (PK–PD) modelling in patients with rheumatoid arthritis (RA). |
| Databáze: | OpenAIRE |
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