Risk factors for noninvasive ventilation failure in patients with acute cardiogenic pulmonary edema: A prospective, observational cohort study
| Autor: | Fusheng Han, Yuhong Mi, Zhixin Cao, Gen Yang, Zujin Luo, Yichong Li, Hangyong He, Yingmin Ma |
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| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Ejection fraction business.industry 030208 emergency & critical care medicine 030204 cardiovascular system & hematology Critical Care and Intensive Care Medicine medicine.disease Intensive care unit law.invention 03 medical and health sciences 0302 clinical medicine law Internal medicine Fraction of inspired oxygen Killip Class IV medicine Cardiology Myocardial infarction Risk factor business Prospective cohort study Cohort study |
| Zdroj: | Journal of Critical Care. 39:238-247 |
| ISSN: | 0883-9441 |
| DOI: | 10.1016/j.jcrc.2017.01.001 |
| Popis: | Purpose We identified risk factors for noninvasive ventilation (NIV) failure in patients with acute cardiogenic pulmonary edema (ACPE). Materials and methods We conducted an observational cohort study over a 3-year period in a 28-bed emergency intensive care unit (EICU) and prospectively included all consecutive patients in whom NIV was attempted as initial ventilatory support for ACPE. The primary outcome variables were NIV failure rate and risk factors for NIV failure. Results Among the 118 patients in the study, NIV failed for 44 (37.3%) patients. Risk factors for NIV failure were Killip class IV (odds ratio [OR], 28.56; 95% confidence interval [CI], 2.17–375.73; p = 0.011), left ventricular ejection fraction (LVEF) Conclusions NIV failure occurred in 37.3% of ACPE patients in a real-world EICU. When patients had Killip class IV, a lower LVEF, a higher BNP, and a more positive fluid balance within 24 h after ACPE, the risk of failure was higher. Trial registration ClinicalTrials.gov identifier NCT02653365. |
| Databáze: | OpenAIRE |
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