Intrasession reproducubility of retinal nerve fibre and macular thickness measurements using Cirrus Fourier‐domain OCT in DM patients without retinopathy

Autor: Isabel Pinilla, E Borque, E Garcia Martin, Miriam Idoipe, S Fernandez-Perez, Mc Egea, E Prieto
Rok vydání: 2011
Předmět:
Zdroj: Acta Ophthalmologica. 89
ISSN: 1755-3768
1755-375X
Popis: Purpose To evaluate the intrasesion reproducibility of retinal thickness and retinal nerve fiber layer (RNFL) measurements in type 1 diabetic subjects without retinopathy using Cirrus Fourier-domain optical coherence tomograph (OCT) (Carl Zeiss Meditec, Inc) Methods 35 patients with diabetes Mellitus (DM) type 1 underwent 3 scans through Cirrus-HD in the same session, separated for 3 minutes between each scan. Each scan included 2 adquision protocols: “Macular Cube 512 x 128” and “Optic Disc Cube 200 x 200”. Descriptive statistics, analysis of variance, intraclass correlation coefficients (ICCs) and coefficients of variation (COV) were calculated for nine areas corresponding to the Early Treatment Diabetic Retinopathy Study an for macular volume, and for quadrants and RNFL clock hours sectors. Results Mean retinal thickness was 298,14 ± 12,76 µm at the first scan, 296,97 ± 12,75 µm at the second scan, and 296,86 ± 12,03 µm at the third scan. Coefficients of variation ranged from 0,7% to 2,2%. Intraclass correlation coefficients ranged from 0.622 to 0.972. Mean RNFL average thickness were 97,28 ± 9,26 µm at the first scan, 96,38 ± 9,98 µm at the second scan, and 95,91 ± 10,11 µm at the third scan. COV ranged from 1,9% to 5,5%. ICC ranged from 0.823 to 0.987. No significant differences were found except in macular central thickness. Conclusion Retinal and RNFL thickness measurements obteined using Cirrus OCT were highly reproducible in type 1 DM patients with low intrassesion variabilities, so it can be consider a valid device for measuring retinal and optic nerve parameters in these patients.
Databáze: OpenAIRE
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