Radical cyclization of ynamides into six- or eight-membered rings. Application to the synthesis of a protoberberine analog

Autor:	Sebastien Balieu, L. Carro, Krimo Toutah, Lise-Marie Chamoreau, Hélène Rousselière, Christine Courillon
Rok vydání:	2011
Předmět:	Chemistry Stereochemistry Radical Organic Chemistry Drug Discovery Organic chemistry Biochemistry Radical cyclization Chemical synthesis
Zdroj:	Tetrahedron Letters. 52:2876-2880
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2011.03.118
Popis:	A straightforward formation of six- and eight-membered rings via the radical cyclization of specifically designed ynamides is reported. This strategy provides a protoberberine analog in only three steps by a radical cyclization cascade.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c6788c37cd1b0e75e5a72f8ebf7c4897 https://doi.org/10.1016/j.tetlet.2011.03.118 Zobrazit plný text záznamu Full Text from ScienceDirect