Tannin antioxidants from Osbeckia chinensis

Autor: Mitsuo Namiki, Jeng-De Su, Shunro Kawakishi, Toshihiko Osawa
Rok vydání: 1988
Předmět:
Zdroj: Phytochemistry. 27:1315-1319
ISSN: 0031-9422
DOI: 10.1016/0031-9422(88)80184-5
Popis: Six hydrolysable tannins, casuarinin ( 1 ), casuariin ( 2 ), punicacortein A ( 3 ), degalloyl-punicacortein A ( 4 ), 2,3-[( S )-4,4′,5,5′,6,6′-hexahydroxydiphenoyl]- d -glucopyranoside ( 5 ), and 4,6-[( S )-4,4′,5,5′,6,6′-hexahydroxydiphenoyl]- d -glucopyranoside ( 6 ), and related compounds, gallic acid, methyl gallate and ellagic acid, were isolated from the methanol extract of Osbeckia chinensis . In order to confirm the structure-activity relationship, the antioxidant activities of these compounds were examined both in the food model and in vitro systems. The antioxidative efficiency, using the thiocyanate and TBA methods, increased in the order of gallic acid 4 ) 3 ) 5 )=( 6 ) 2 ) 1 )=BHA in vitro antioxidant order is α-tocopherol 4 ) 3 )=( 5 )=( 6 )=ellagic acid 2 ) 1 ) in the rabbit erythrocyte membrane ghost system, and ellagic acid 4 ) 3 )=( 5 )=( 6 ) 2 ) 1 ) = α-tocopherol in the rat liver microsome system.
Databáze: OpenAIRE