Asthma associated with pesticide exposure among women in rural Western Cape of South Africa

Autor: Vuyelwa Ndlovu, Mohamed F. Jeebhay, Mohamed Aqiel Dalvie
Rok vydání: 2014
Předmět:
Zdroj: American Journal of Industrial Medicine. 57:1331-1343
ISSN: 0271-3586
DOI: 10.1002/ajim.22384
Popis: Background Few studies have investigated asthma and pesticides among women farm workers in developing countries. Methods A cross-sectional study was conducted to investigate the association between pesticides and asthma among rural women (n ¼211). Outcome measurements included respiratory symptoms (European Community Respiratory Health Survey questionnaire), immunological status (Phadiatop, serum IgE to mite allergens) and lower airway inflammation (fractional exhaled nitric oxide (FeNO) levels). Exposure variables included self-reported pesticide exposure and whole blood cholinesterase (ChE). Results The prevalence of ocular-nasal symptoms (ONS), doctor-diagnosed asthma and current asthma was 24%, 11%, and 6% respectively. ONS was positively associated with re-entering a sprayed field (OR ¼2.97; CI: 0.93–9.50). Asthma symptom score was associated with low ChE (OR ¼1.93; CI: 1.09–3.44). Participants with high FeNO (>50ppb) also had an elevated odds of having low ChE (OR ¼4.8; CI: 0.80–28.00). Conclusion Pesticide exposure among women farm workers is associated with increased risk of ocular nasal symptoms and an elevated asthma symptom score. Am. J. Ind. Med. 57:1331–1343, 2014. 2014 Wiley Periodicals, Inc.
Databáze: OpenAIRE