Antitumor activity of liposomal aclarubicin in vitro and in vivo

Autor:	Navashin Sm, Viadro Mm
Rok vydání:	1991
Předmět:	Antitumor activity Liposome Anthracycline Chemistry medicine.drug_class Antibiotics General Medicine Pharmacology General Biochemistry Genetics and Molecular Biology In vitro In vivo Toxicity medicine Aclarubicin medicine.drug
Zdroj:	Bulletin of Experimental Biology and Medicine. 112:1634-1636
ISSN:	1573-8221 0007-4888
Popis:	Study on antitumor activity of free and liposomal anthracycline antibiotic aclarubicin in vitro and in vivo showed that liposomal aclarubicin was characterised by activity against ascitic Ehrlich carcinoma comparable to that of free aclarubicin when used in a dose of 25 mg/kg. Liposomal antibiotic had a more pronounced antimetastatic action and showed no toxicity (in a dose of 30 mg/kg). Liposomal aclarubicin had a higher activating capacity with respect to the macrophage tumoricidal properties.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c62068d7239f9ad811526736ab209f87 https://doi.org/10.1007/bf00840434 Zobrazit plný text záznamu Full text from SpringerLink