Chromium-mediated β-lactone synthesis using ultrasonication

Autor:	William J. Kerr, Nicola Murdoch Heron, David Middlemiss, Sharon McKendry, John J. Caldwell, Joseph P. A. Harrity
Rok vydání:	1999
Předmět:	Diene Sonication Aryl Organic Chemistry chemistry.chemical_element Biochemistry Sonochemistry chemistry.chemical_compound Chromium Adsorption chemistry Lactone synthesis Drug Discovery Alkoxy group Organic chemistry
Zdroj:	Tetrahedron Letters. 40:3481-3484
ISSN:	0040-4039
Popis:	The reaction of chromium aryl(alkoxy)carbenes with propargylic alcohols has been investigated under dry state adsorption and ultrasound conditions. When compared to the corresponding thermal processes, the developed sonication reactions afford good yields of β-lactone products over generally shorter reaction times. Dry state adsorption affords diene products which are also obtained from the corresponding β-lactones. Reactions of Cr-aryl(alkoxy)carbenes and propargylic alcohols proceed rapidly under sonication conditions to afford good yields of functionalised β-lactones. Download : Download full-size image
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c5fabefe90a021a41a0ed3a9dec2b0b6 https://doi.org/10.1016/s0040-4039(99)00429-3 Zobrazit plný text záznamu Full Text from ScienceDirect