Spontaneous and Experimental Hepatitis A in Old World Monkeys

Autor:	Z.V. Shevtsova, B.A. Lapin, N.V. Doroshenko, R.I. Krilova, L.I. Korzaja, I.B. Lomovskaya, Z.N. Dzhelieva, G.K. Zairov, V.M. Stakhanova, E.G. Belova, L.A. Sazhchenko
Rok vydání:	1988
Předmět:	Old World General Veterinary biology viruses animal diseases virus diseases Hepatitis A Disease biology.organism_classification medicine.disease Chlorocebus aethiops Virology Cercopithecus aethiops Human hepatitis A virus Serology Immunology medicine Animal Science and Zoology Viral disease
Zdroj:	Journal of Medical Primatology. 17:177-194
ISSN:	1600-0684 0047-2565
DOI:	10.1111/j.1600-0684.1988.tb00380.x
Popis:	Virologic, serologic, biochemical, and morphological data characterizing spontaneous hepatitis A (HA) in cynomolgus macaques (Macaca fascicularis) and green monkeys (Cercopithecus aethiops) are reported. Experimental HA was induced in macaques as a result of infection with human hepatitis A virus (HAV-h). Disease similar to human HA was induced in cynomolgus macaques by HAV isolates from spontaneously sick rhesus (M. mulatta) and green monkeys. This experimental model of HA in macaques can be used for vaccine and anti-viral preparation testing.
Databáze:	OpenAIRE
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