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Objetives: Malaria is a health problems in the world. WHO recomended several insecticides for Indoor residual spraying. Due to continious use of insecticides , the malaria vectors show resistant to different groups of insecticides. The aim of study was to evaluate the new mixture of pesticides Fludora® Fusion) (a mixture of deltamethrin and clothianidin) for indoor residual spraying against insecticide resistant strain of Anopheles stephensi in a malarious area in Bandar Abbas, Iran.Materials and Methods: The residual effect of Fludora® fusion (WP-SB 562.5 g/kg in 100g wsb) was evauated on various local surfaces of rooms such as mud and plaster as well as thatch roofs and wooden. Wordl Health Organization (WHO) standard cones using contact bioassays were carried out using laboratory reared, carbamate and pyrethroid resistant strain of Anopheles stephensi . Contact bioassays were carried out on sprayed surfaces. The cut of point of WHO is 80% mortality. Relative humidity and temperature of the test rooms has been recorded during the bioassay experimentsResults: Contact bioassay tests was carried out on days 1, 5,15,30, 60, 90, 120,150, 180,210,240,290 days after application . The mortality in all surfaces until 8 months is more than 80%. Mortality rate after 9 months on plaster and mud was more than 80%. The results form cement and wood was less than 80% . Discussion and conclusión: Indoor residual spraying with Fludora® Fusion induced high and prolonged mortality of carbamate and pyrethroid-resistant malaria vectors for 9 months mostly due to the clothianidin component. This mixture is an important Integrated Vector Management for control of resistant malaria vector. |
