| Autor: |
E. J. Hoffman, M. E. Phelps, J. B. Barton, S.-C. Huang |
| Rok vydání: |
1983 |
| Předmět: |
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| Zdroj: |
Positron Emission Tomography of the Brain ISBN: 9783540121305 |
| Popis: |
The purpose of this chapter is to provide an analysis of some of the new design concepts for instrumentation in positron tomography as it specifically relates to studies of the brain. Since positron tomography is an imaging modality it is useful to have a picture of the state of the art of instrumentation and a picture of the possible improvement that could be provided by future instruments. This improvement can be seen in simulations of brain images, which were created by digitizing the gray and white matter distributions of actual brain slices, assigning isotope concentrations to the structures (a 4 to 1 gray/white ratio), and then imposing the resolution blurring and statistical noise of an actual tomograph upon this ideal data (Mazziotta et al. 1981; Phelps et al. 1982). Examples of such a simulation are shown in Fig. 1. The lower two images are comparable in resolution to presentday-tomographs with 9–12 mm FWHM resolution (Hoffman et al. 1981, 1982). The upper two images constitute the design goal for future positron tomography systems with intrinsic resolutions of 2–4 mm FWHM. The complexity and small size of many of the structures in the brain make it obvious that the highest possible resolution should be a primary design goal for any brain imaging system. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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