| Autor: |
António Miguel Morgado, Maria João Quadrado, S. Gouveia, P. M. R. Cardoso, Iulian Otel, Susana F. Silva, José Silvestre Silva, Jose P.P. Domingues, Leonor Gomes, Manuela Carvalheiro |
| Rok vydání: |
2013 |
| Předmět: |
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| Zdroj: |
2013 IEEE 3rd Portuguese Meeting in Bioengineering (ENBENG). |
| DOI: |
10.1109/enbeng.2013.6518436 |
| Popis: |
Diabetic peripheral neuropathy is one of the most common complications of diabetes. It affects 50% of the patients after 25 years of disease. Its early diagnosis and accurate assessment are important to define the higher risk patients. A non-invasive technique for its assessment was developed. The technique is based on morphometric parameters of corneal nerves, obtained by analysis of corneal confocal microscopy images of the sub-basal nerve plexus. We examined 12 type-2 diabetic patients (average age: 58±10 years) and 8 healthy controls (54±7 years). We found differences statistically significant for nerve length, density, width and branching parameters, when we compare individuals with and without neuropathy. The corneal sub-basal nerve plexus morphology has the potential for identifying the presence of diabetic peripheral neuropathy and evaluating its severity. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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