Automated measurement of retinal vascular caliber and arteriovenous ratio in type 2 diabetic patients without retinopathy

Autor: Dw Lee, Jh Bae, Jm Kim, Hj Jang, Cy Choi
Rok vydání: 2012
Předmět:
Zdroj: Acta Ophthalmologica. 90
ISSN: 1755-375X
Popis: Purpose To determine the retinal vascular caliber and arteriovenous ratio (AVR) in type 2 diabetic patients without retinopathy. Methods We retrospectively reviewed the medical records of 70 patients diagnosed as type 2 diabetes without retinopathy. Digital fundus photographs of the right eye were selected for measurement. The caliber of all retinal vessels passing through an area 0.5 to 1 disc diameter around the optic disc was measured using automated computer software (Zeiss AV ratio). Seventy seven age- and sex-matched healthy subjects were included in the study as a control. Results The mean AVR was 0.801 ± 0.068 in the diabetic patients compared to 0.762 ± 0.054 in the control group (P < 0.001). Higher AVR was significantly associated with increasing blood HbA1c levels (r2 = 0.106, P = 0.006). However, there was no significant correlation between AVR and body mass index (P = 0.478). Conclusion The rise in AVR seems to be an early feature of retinal vascular caliber in type 2 diabetes and correlates with an elevated blood HbA1c level.
Databáze: OpenAIRE