| Popis: |
A simple, cost efective and green method was presented for the synthesis of coumarin bis sulfonamides. 17 novel coumarin sulfonamides were synthesized in good to high yield and purity in six steps starting from 2-amino thiazole, aniline and 4-methoxy aniline. All of the reactions have been done under green conditions without using any hazardous solvent.Also, the anti-bacterial properties of the synthesized sulfonamides were investigated using two strains of Staphylococcus (gram-positive) and Escherichia coli (gram-negative) bacteria. |
