In vivo antidiarrheal study of ethanolic extracts of Mikania cordata and Litsea monopetala leaves

Autor:	Md. Lukman Hakim, Fatema Nasrin
Rok vydání:	2015
Předmět:	Pharmacology Loperamide Traditional medicine Biology biology.organism_classification Mikania cordata Diarrhea Oral administration In vivo Castor oil medicine Litsea monopetala medicine.symptom Feces medicine.drug
Zdroj:	Bangladesh Journal of Pharmacology. 10:562
ISSN:	1991-0088
DOI:	10.3329/bjp.v10i3.23402
Popis:	In this study the antidiarrheal activity of ethanolic extracts of the leaves of Mikania cordata and Litsea monopetala was evaluated. Diarrhea was induced in mice by oral administration of castor oil (0.5 mL) 30 min after the administration of the extracts. During a 4 hour study the number of diarrheal feces and percentage inhibition of the extracts (200 and 400 mg/kg body weight) was determined. Loperamide (3 mg/kg body weight) served as standard and belonged to the positive control group. The extracts exhibited potent antidiarrheal activity as well as achieved statistically significant p value (pL. monopetala. So, the study corroborates the significant antidiarrheal activity of M. cordata and L. monopetala leaf extracts and raises the demand of further sophisticated investigation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c574848ed9bc63c9c9b324565415ea40 https://doi.org/10.3329/bjp.v10i3.23402 Zobrazit plný text záznamu Plný text ve formátu PDF