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Introduction Exposure to fine particulate matter (≤ 2.5 micrometres; PM2.5) had been associatted to subclinic atherosclerosis and cardiovascular disease (CVD). However, the effect of PM2.5 on the plasma lipid fractions, which might be mediating its associations with CVD, is unknown. Methods Cross-sectional study in adult population (older than 40 years, non-smokers, with no previous CVD) living in two urban areas of Bucaramanga, Colombia. We estimated the houses indoor PM2.5 concentration by using gravimetric sampling pumps (Casella Cel – TUFF) and recorded the average measurements during two consecutive days. We obtained from participants sociodemographic information, waist perimeter and fasting lipid profile. We used a multiple regression to determine the association between PM2.5 and each lipid profile component while adjusting for covariables. Results We have enrolled 270 participants (mean age: 57.4 years; 21% men; 80% 18h living indoors). The mean indoor PM2.5 concnetration was 25.3 µg/m3 (range: 2.... |
