P02-393 - Genders Differences In Opiate-Dependent Patients Undergoing A Replacement Therapy Program In Spain: The Proteus Study

Autor:	J. Llaudó, G. Fuste, Laia Miquel, B. Box, N. Martínez, Laia Rodríguez-Cintas, Miquel Casas, Carlos Roncero
Rok vydání:	2010
Předmět:	medicine.medical_specialty education.field_of_study Pediatrics business.industry Population Spanish population Psychiatry and Mental health Informed consent Physical therapy Medicine Dual diagnosis Observational study Opiate business education Opiate dependence Methadone medicine.drug
Zdroj:	European Psychiatry. 25:1-1
ISSN:	1778-3585 0924-9338
Popis:	IntroductionThere are 80.000 patients undergoing replacement opiate programs in Spain, mainly methadone. Gender differences and the ratio of dual diagnosis in this population are unknown.ObjectivesTo describe gender differences in the current therapeutic management of opiate-dependent patients undergoing a replacement therapy program in Spain.Methods624 patients from 74 centers in Spain were included between September 2008 and February 2009 in an observational, cross-sectional, multicenter study. Patients were ≥ 18 years, had a diagnosis of opiate dependence according to DSM-IV-TR criteria, were currently scheduled in a replacement therapy program in Spain and were given written informed consent.ResultsOnly 16% of patients were female. Methadone average doses were significantly higher in man (57,59mg ± (SD 46,77) vs 52,81mg ± (SD 50,81) (p< 0.05)). Most women were caretaken by their partner (56.8% vs 34,2%) and man by their parents (61,6% vs 37,8) p< 0,05.Women were found to have significantly more sexual disorders than men (6% versus 2%; p=0.0316); but less delirium, dementia, amnesic and other cognitive disorders (none versus 6%; p=0.0486); schizophrenia and other psychotic disorders (3% versus 13%; p=0.0226); and adaptive disorders (2% versus 9%; 0.0427). No significant differences were found between sexes for other psychiatric comorbidities.ConclusionThe ratio between men and women was close to 5/1, being bigger than that in the general opiate dependent Spanish population. Dual diagnosis rates vary by gender, but not in the number of diagnosis in Axis I or II. Gender differences must be considered when planning dependence services as women.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c54b6af11e954de7e90a31ea978d8b14 https://doi.org/10.1016/s0924-9338(10)71395-x Zobrazit plný text záznamu