Role of polyethyleneimine (PEI) in synthesis of zinc oxide nanoparticles and their cytotoxicity effects

Autor: K.D. Verma, Seyed Jamal Alavi, Majid Darroudi, Reza Kazemi Oskuee, Niloofar Khalili
Rok vydání: 2015
Předmět:
Zdroj: Ceramics International. 41:10222-10226
ISSN: 0272-8842
Popis: Monodispersed zinc oxide nanoparticles (ZnO-NPs) were synthesized by a simple sol–gel method. In this process, polyethyleneimine (PEI) was used as a polymeric matrix and mild reaction conditions. The PEI acted as a stabilizing or capping agent and polymeric template for preparing ZnO-NPs. The ZnO-NPs were successfully grown at different calcination temperatures, and their crystallite structures were characterized using various methods, including TEM, PXRD, FTIR, and TGA/DTA techniques. The PXRD analysis revealed wurtzite hexagonal ZnO with preferential orientation at (101) reflection plane. Spherical ZnO-NPs were synthesized and its TEM image showed the formation of nanopowders in size of about 25 nm, while dose dependent toxicity with non-toxic effect of concentration below 6.25 µg/mL was observed in the studies of in vitro cytotoxicity on neuro2A cells.
Databáze: OpenAIRE