Supramolecular Complex of 20-Hydroxyecdysone-3-acetate with β-Cyclodextrin and Its Biological Activity
| Autor: | T. M. Seilkhanov, O. T. Seilkhanov, Pavel Drašar, S. M. Adekenov, K. M. Turdybekov, B. I. Tuleuov, B. S. Temirgaziev, R. B. Seydakhmetova, A. M. Kozhanova |
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| Rok vydání: | 2020 |
| Předmět: |
chemistry.chemical_classification
Cyclodextrin 010405 organic chemistry Chemistry Spatial structure 20-Hydroxyecdysone Supramolecular chemistry Biological activity General Chemistry 010402 general chemistry 01 natural sciences Combinatorial chemistry 0104 chemical sciences chemistry.chemical_compound |
| Zdroj: | Russian Journal of General Chemistry. 90:2258-2263 |
| ISSN: | 1608-3350 1070-3632 |
| DOI: | 10.1134/s1070363220120075 |
| Popis: | In order to obtain new potentially bioactive substances and to investigate the effect of bulky functional groups on the formation of supramolecular complexes, 20-hydroxyecdysone triacetate has been synthesized, its spatial structure has been determined, and its complexation with β-cyclodextrin has been studied by means of NMR. The anti-inflammatory activity of the obtained water-soluble complex has been assessed. |
| Databáze: | OpenAIRE |
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