ASSOCIATION OF CELIAC DISEASES WITH SEVERE ACUTE MALNUTRITION CHILDREN, AT TERTIARY CARE CENTRE: - A PROSPECTIVE STUDY
| Autor: | Sameer Jagrwal, Manish Singhal, Pooja Sharma, Prasun Bhattacharjee, Kapil Shrimali |
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| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | International Journal of Medical and Biomedical Studies. 5 |
| ISSN: | 2589-8698 2589-868X |
| Popis: | Introduction: Celiac disease (CD) may be an underlying cause of malnutrition. Aim: The objective of this study was to find out the seroprevalence of CD in children suffering from severe acute malnutrition (SAM) in age group of 1–5 years. Materials and Methods: This was a prospective, observational, hospital-based study carried out at Malnutrition Treatment Centre attached with the ananta institute of medical science & research center Rajsamand, Rajasthan, from February 2019 to January 2020. A total of 220 children with SAM were enrolled and screened for CD on the basis of celiac serology (tissue transglutaminase [tTg]-immunoglobulin A/G [IgA/IgG]). Results: Celiac serology was positivity in 60 (27.28%) cases; out of total 60 seropositive cases, 28 (46.66%) cases were seropositive for both tTg-IgA and IgG, while only tTg-IgA and only tTg-IgG were positive in 18 (30%) and 14 (23.33%) cases, respectively. Mean serotiter of serum tTg-IgA and IgG in seropositive cases was 134.01±198.74 and 49.05±25.74 unit/ml. Conclusions: High seroprevalence of CD in SAM should be taken as alert as CD may be an underlying cause and responsible for malnutrition. These children should be screened by celiac serology (tTg-IgA/IgG) to rule out CD. Key words: Celiac disease, Seroprevalence, Severe acute malnutrition |
| Databáze: | OpenAIRE |
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