Phytochemical content and antioxidant activities of pomelo peel extract

Autor:	Asser Ashraf Ahmad, Shaimaa M. Mohammed, Ihab Ibrahim Al Khalifa, Zead Helmi Mahmoud Abudayeh
Rok vydání:	2019
Předmět:	Pharmacology chemistry.chemical_classification Ethanol Antioxidant Vitamin C DPPH medicine.medical_treatment 0211 other engineering and technologies food and beverages 02 engineering and technology Ascorbic acid 01 natural sciences 0104 chemical sciences 010404 medicinal & biomolecular chemistry chemistry.chemical_compound chemistry Phytochemical 021105 building & construction Drug Discovery medicine Food science Carotenoid IC50
Zdroj:	Pharmacognosy Research. 11:244
ISSN:	0974-8490
Popis:	Background: There is an increasing interest in the antioxidant measurement of some plant constituents. Plant component, especially fruit, has antioxidant components which are safe, economic, and powerful to reduce oxidative stress and replace synthetic ones. Objective: To quantitatively measure the flavonoids, Vitamin C, and carotenoid content of hydroalcoholic extract and to estimate the antioxidant activity of pomelo peel extract (PPE) and minimum inhibitory concentration 50% (IC50) of the extract using 2,2-diphenyl-1-picrylhydrazyl (DPPH) ethanolic solution. Materials and Methods: Hydroalcoholic PPE was prepared; total flavonoids using aluminum chloride method, Vitamin C using thiourea and 2,4-dinitrophenylhydrazine method, and carotenoid content of the extract were estimated using 95% ethanol solution. All measurements were estimated using ultraviolet–visible spectrophotometer. Antioxidant activity and IC50of PPE were measured using DPPH method. Results: Flavonoids, Vitamin C, and carotenoid content were measured as 21.20 mg/100 g, 15.13 mg/100 g, and 62.98 μg/g, respectively, of dry PPE. The DPPH radical scavenging activity exhibits a significant dose-dependent inhibition of DPPH radical color, with IC50being at a concentration of 68.55 μg/ml of the extract, comparable to 55.87 μg/ml IC50of Vitamin C standard antioxidant. Conclusion: From the study results, we could conclude that pomelo peel possesses high antioxidant properties and it is potentially rich sources of natural antioxidants.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c50280db350044189b77c4035295ae91 https://doi.org/10.4103/pr.pr_180_18 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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