Mechanism of Discordant Cardiac Xenograft Rejection — An Alternative View Based on Ultrastructural Observations
Autor: | S. Aziz, D. Thorning, K. Suzuki |
---|---|
Rok vydání: | 1997 |
Předmět: | |
Zdroj: | Xenotransplantation ISBN: 9783642644603 |
DOI: | 10.1007/978-3-642-60572-7_19 |
Popis: | In contradistinction to organ transplants between closely related (concordant) species, where rejection appears to be mediated largely by cellular immune reactions, rejection following transplantation involving widely disparate (discordant) species appears to be mediated largely by humoral mechanisms [1, 2]. Pigs are a potential source of donor organs for human xenotransplantation, and various experimental models have been used to study pig organ rejection after such procedures [3]. |
Databáze: | OpenAIRE |
Externí odkaz: |