Aqueous extract of Solanum macrocarpon Linn leaves abates hyperglycaemia and expression of glucose transporters gene in alloxan-induced diabetic rats
| Autor: | I L Ekakitie, Abidemi Paul Kappo, O. S. Owero-ozeze, Basiru Olaitan Ajiboye, Babatunji Emmanuel Oyinloye, Mary Abiola Okesola, Oluwafemi Adeleke Ojo |
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| Rok vydání: | 2020 |
| Předmět: |
chemistry.chemical_classification
Antioxidant biology Glycogen Chemistry Endocrinology Diabetes and Metabolism medicine.medical_treatment Glucose transporter 030209 endocrinology & metabolism Solanum macrocarpon Pharmacology biology.organism_classification medicine.disease Lipid peroxidation 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Endocrinology Enzyme 030220 oncology & carcinogenesis Alloxan Diabetes mellitus medicine |
| Zdroj: | Journal of Endocrinological Investigation. 44:265-276 |
| ISSN: | 1720-8386 |
| DOI: | 10.1007/s40618-020-01280-y |
| Popis: | In this study, antihyperglycaemic and level of gene expression of glucose transporters in alloxan-induced diabetic rats administered aqueous extract of S. macrocarpon leaves were assessed. Diabetes was induced by a single intraperitoneal (I.P) injection of freshly prepared alloxan. The animals were divided into six groups, euthanized on the fourteenth day of the experiment and different hyperglycaemic parameters were evaluated. Administration of different doses of the plant extract significantly (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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