Clonorchis sinensisova in bile juice cytology from a patient with severe hyperbilirubinemia and portal vein thrombosis
| Autor: | Keiichi Fujiya, Ja-Mun Chong, Hideaki Ganno, Masayuki Ando |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Abdominal pain
medicine.medical_specialty Histology Gastroenterology Pathology and Forensic Medicine 03 medical and health sciences 0302 clinical medicine Internal medicine medicine 030212 general & internal medicine Thrombus Clonorchis sinensis biology business.industry General Medicine Gallstones Jaundice medicine.disease biology.organism_classification Portal vein thrombosis Surgery Venous thrombosis Clonorchiasis 030211 gastroenterology & hepatology medicine.symptom business |
| Zdroj: | Diagnostic Cytopathology. 44:223-225 |
| ISSN: | 8755-1039 |
| DOI: | 10.1002/dc.23400 |
| Popis: | Infection with the trematode Clonorchis sinensis is the most common human fluke infection in East Asian populations. Although this infection is associated with obstructive jaundice or choledocholithiasis, portal vein thrombosis has not been reported. Here, we report the first case of a 60-year-old man who had both C. sinensis infection and portal vein thrombosis with severe hyperbilirubinemia (75.4 mg/dl). He initially presented with abdominal pain and jaundice. Computed tomography revealed gallstones, common bile duct calculus, and thrombus in the left main branch of the portal vein. A nasobiliary tube was inserted under endoscopic retrograde cholangiography. Cytology of the bile juice revealed many C. sinensis eggs. The abdominal pain and jaundice improved following choledocholithotomy and combination treatment with a chemotherapeutic agent and anti-coagulant. This case suggests that inflammation around the portal vein as a result of C. sinensis infection has the potential to evoke portal vein thrombosis. Such cases should be treated with both a chemotherapeutic agent and anti-coagulant therapy. In conclusion, the possibility of infection with C. sinensis should be considered in patients presenting with hyperbilirubinemia and portal vein thrombosis, particularly in East Asian populations. |
| Databáze: | OpenAIRE |
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