Glyt-1 expression in cultured human Müller cells and intact retinae

Autor:	David V. Pow, Peter Reye, Philip L. Penfold
Rok vydání:	2001
Předmět:	Retina Immunocytochemistry Glutamate receptor Transporter Biology In vitro Cell biology Glycine transporter Cellular and Molecular Neuroscience medicine.anatomical_structure Neurology In vivo medicine Neuroglia sense organs Neuroscience
Zdroj:	Glia. 34:311-315
ISSN:	0894-1491
DOI:	10.1002/glia.1064
Popis:	In this study, we demonstrate that Muller cells cultured from human retinas are capable of strongly expressing the glycine transporter Glyt-1 as assessed by immunocytochemistry. By contrast, intact normal and pathological human retinas exhibit Glyt-1 immunoreactivity only in neurons. These data suggest that Glyt-1 expression in cultured Muller cells is an epiphenomenon associated with culturing in vitro, rather than a normal physiological or even pathophysiological phenomenon in vivo.
Databáze:	OpenAIRE
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