Elevated Thromboxane Levels in the Rat during Endotoxic Shock

Autor:	Perry V. Halushka, Wise Wc, James A. Cook
Rok vydání:	1980
Předmět:	chemistry.chemical_classification medicine.medical_specialty Thromboxane medicine.medical_treatment Prostaglandin Fatty acid Radioimmunoassay General Medicine Prostanoic acid Thromboxane B2 chemistry.chemical_compound Thromboxane A2 Endocrinology chemistry Internal medicine medicine Prostaglandin E
Zdroj:	Journal of Clinical Investigation. 65:227-230
ISSN:	0021-9738
DOI:	10.1172/jci109655
Popis:	The potential deleterious role of the proaggregatory vasoconstrictor, thromboxane A(2), in endotoxic shock was investigated in rats. Plasma thromboxane A(2) was determined by radioimmunoassay of its stable metabolite thromboxane B(2). After intravenous administration of Salmonella enteritidis endotoxin (20 mg/kg), plasma thromboxane B(2) levels increased from nondetectable levels (
Databáze:	OpenAIRE
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