Dielectrophoresis-enabled surface enhanced Raman scattering on gold-decorated polystyrene microparticle in micro-optofluidic devices for high-sensitive detection
Autor: | Takao Fukuoka, Ryohei Hara, Ryo Takahashi, Yuichi Utsumi, Akinobu Yamaguchi |
---|---|
Rok vydání: | 2016 |
Předmět: |
Analyte
Materials science Nanotechnology 02 engineering and technology 010402 general chemistry High sensitive 01 natural sciences chemistry.chemical_compound symbols.namesake Materials Chemistry Electrical and Electronic Engineering Microparticle Instrumentation Metals and Alloys Dielectrophoresis 021001 nanoscience & nanotechnology Condensed Matter Physics 0104 chemical sciences Surfaces Coatings and Films Electronic Optical and Magnetic Materials chemistry symbols DLVO theory Polystyrene 0210 nano-technology Raman spectroscopy Raman scattering |
Zdroj: | Sensors and Actuators B: Chemical. 230:94-100 |
ISSN: | 0925-4005 |
Popis: | We have developed a method to fabricate higher order surface enhanced Raman scattering (SERS) active structure with gold-decorated polystyrene microparticles (Au/PS microparticles) to serve a wide range of applications in life science and environmental analysis using alternating-current dielectrophoresis (DEP). It is within several tens of seconds to form or gather the SERS—active ‘hot spots’ and analyte. The immobilization of Au/PS microparticles can be demonstrated and qualitatively explained by DLVO and DEP calculation. Our method enables us to detect 4, 4′-bipyridine (4bpy) at 100 pM by an easy operation of in situ SERS platform using fiber-type simple Raman spectrometer. This platform can easily generate SERS-active ‘hot spots’ with SERS enhancement factor ∼ 10 8 in specific region on demand. |
Databáze: | OpenAIRE |
Externí odkaz: |