Long term persistence of IgE anti-hepatitis A virus antibodies in adult serum post vaccination. (113.9)

Autor:	Martin Bluth, Dina Kokh, Weili Zhou, Fadumo Rirash, Tamar Smith-Norowitz
Rok vydání:	2012
Předmět:	Immunology Immunology and Allergy
Zdroj:	The Journal of Immunology. 188:113.9-113.9
ISSN:	1550-6606 0022-1767
Popis:	Rationale: The role of IgE in immunity against Hepatitis A has not been studied. Methods. Serum was obtained from an adult who was vaccinated with Hepatitis A virus (HAV) (Havrix®) in 2005 and again in 2009 and compared with pre vaccination status and natural HAV infection. Serum was assessed for the presence of IgE anti-HAV antibody (modified Immunoblot/ELISA, spectrophotometry) over seven years post vaccination and compared with IgG and IgM virus specific antibodies.. Results. Serum obtained from HAV adult contained IgE anti-virus antibodies which increased over 1.5 years post initial vaccination. In contrast, serum levels of IgE anti-HAV antibodies increased 6 fold two years after 2nd vaccine booster compared with pre-booster levels (1.2OD450 vs 0.21OD450, p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c4cfca6f3036a7d9a59b3ae1325bffff https://doi.org/10.4049/jimmunol.188.supp.113.9 Zobrazit plný text záznamu