Elevated Incidence of Atrial Fibrillation and Stroke in Patients With Atrial Flutter—A Population-Based Study
| Autor: | Damian P. Redfearn, Krista Bray Jenkyn, Britney Allen, Peter Leong-Sit, Lorne J. Gula, Salimah Z. Shariff, Allan C. Skanes |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
congenital
hereditary and neonatal diseases and abnormalities medicine.medical_specialty medicine.medical_treatment Population Catheter ablation 030204 cardiovascular system & hematology Rate ratio 03 medical and health sciences 0302 clinical medicine Typical atrial flutter Internal medicine medicine cardiovascular diseases 030212 general & internal medicine education Stroke education.field_of_study business.industry Atrial fibrillation Retrospective cohort study pathological conditions signs and symptoms medicine.disease cardiovascular system Cardiology Cardiology and Cardiovascular Medicine business Atrial flutter |
| Zdroj: | Canadian Journal of Cardiology. 34:774-783 |
| ISSN: | 0828-282X |
| DOI: | 10.1016/j.cjca.2018.01.001 |
| Popis: | Background The risk of stroke from atrial flutter and its relationship with progression to atrial fibrillation (AF) is unclear. This study describes the incidence of AF and stroke in patients with atrial flutter, and whether atrial flutter ablation attenuates the incidence of AF and stroke. Methods We performed a population-based retrospective cohort study of adults with typical atrial flutter with no AF history. Using linked health administrative databases we defined 3 cohorts: (1) adult patients diagnosed with new isolated atrial flutter; (2) a contemporary, 1-to-1 matched cohort from the Ontario population; and (3) patients with isolated atrial flutter who underwent atrial flutter ablation. Results A total of 9339 new typical atrial flutter patients were identified and 7248 were matched to general population subjects. Over the 3-year follow-up, AF occurred in 40.4% of patients with atrial flutter, and 3.3% of the matched general population (rate ratio, 12.2; P P Conclusions Patients with isolated atrial flutter develop AF and stroke at a higher rate than the general population. Catheter ablation reduces but does not eliminate future AF incidence and stroke risk and continued anticoagulation after successful atrial flutter ablation might therefore be warranted. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect