Determination of minimum inhibitory concentration of Azithromycin, Ofloxacin and Ceftriaxone in Ciprofloxacin resistant Salmonella causing enteric fever

Autor:	Ahmed Abu Saleh, Tanzima Begum, Khandker Md Nurus Sabah, Shamima Kawser, Md. Ruhul Amin Miah
Rok vydání:	2013
Předmět:	Salmonella medicine.drug_class business.industry Cephalosporin Antibiotics bacterial infections and mycoses medicine.disease_cause Azithromycin Virology Microbiology Ciprofloxacin Minimum inhibitory concentration medicine Ceftriaxone General Materials Science Ofloxacin business medicine.drug
Zdroj:	Bangladesh Journal of Medical Microbiology. 5:26-30
ISSN:	2072-3105 2070-1810
DOI:	10.3329/bjmm.v5i1.15818
Popis:	The therapeutic alternatives available for use against ciprofloxacin resistant enteric fever isolates in an endemic area are limited. The antibiotics currently available are the quinolones, third-generation cephalosporins and azithromycin. In this study, the MICs of various drugs were determined for 100 enteric fever isolates (72 Salmonella enterica serovar typhi and 28 Salmonella enterica serovar paratyphi A ). Ciprofloxacin resistant (1oo%) Salmonella strains were sensitive to ofloxacin and ceftriaxone showing MICs of 0.0078-2 g /ml and 0.0156-2g /ml respectively. Salmonella strains (98%) had MIC values 1-32 g /ml for azithromycin. These results indicate that ofloxacin and ceftriaxone may be convenient alternative antimicrobial agents for Salmonella isolates.DOI: http://dx.doi.org/10.3329/bjmm.v5i1.15818 Bangladesh J Med Microbiol 2011; 05 (01): 26-30
Databáze:	OpenAIRE
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