IgG4-Related Disease and the Salivary Glands
| Autor: | S. Andrew Skillington, M. Allison Ogden |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Systemic disease
Pathology medicine.medical_specialty business.industry Soft tissue General Medicine Disease medicine.disease Sialadenitis Pathophysiology 03 medical and health sciences 0302 clinical medicine stomatognathic system Otorhinolaryngology Fibrosis Salivary Gland Diseases 030220 oncology & carcinogenesis parasitic diseases medicine IgG4-related disease 030223 otorhinolaryngology business |
| Zdroj: | Otolaryngologic Clinics of North America. 54:497-508 |
| ISSN: | 0030-6665 |
| DOI: | 10.1016/j.otc.2021.02.002 |
| Popis: | IgG4-related disease is a rare, immune-mediated, systemic disease that is characterized by soft tissue lymphocyte infiltration and resultant fibrosis. The salivary glands are among the most commonly affected organs. Patients present with subacute submandibular and/or parotid swelling and sialadenitis. Diagnosis incorporates clinical, serologic, radiologic, and pathologic findings. Most cases respond quickly to systemic glucocorticoids. IgG4-related disease mimics many infectious, inflammatory, and neoplastic diseases. Therefore, IgG4-related disease is frequently misdiagnosed. A knowledge of the pathophysiology, diagnosis, and management of IgG4-related disease is important for providers who treat salivary gland diseases. |
| Databáze: | OpenAIRE |
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