Effect of toxic extract from the outercoat of the fruit of T. africana on intestinal d-glucose transport in rat in vivo
| Autor: | R.Ola Lawal, O. Bassir, O.L. Oke |
|---|---|
| Rok vydání: | 1989 |
| Předmět: |
medicine.medical_specialty
Glucose transporter food and beverages Ileum General Medicine Biology Pharmacology Analytical Chemistry chemistry.chemical_compound medicine.anatomical_structure Endocrinology chemistry In vivo Polyphenol D-Glucose Internal medicine medicine Saline extract Inhibitory effect Food Science |
| Zdroj: | Food Chemistry. 32:125-134 |
| ISSN: | 0308-8146 |
| Popis: | A saline extract solution from the outercoat of the fruit of T. africana was prepared and tested for its total polyphenolic content and effect on intestinal d-glucose transport across rat ileum in vivo. Intestinal d-glucose transport was significantly reduced (P < 0·001) by the presence of the outercoat-extract in the intestinal loop. This extract, which has appreciable polyphenolic content, caused both a reversible and a lasting inhibitory effect on glucose transport. Polyamide treatment of the extract decreased its ability to inhibit glucose transport but the inhibitory effect was not completely abolished by the treatment, further suggesting the presence of some other anti-absorptive factor(s) in the outercoat of the fruit of T. africana. |
| Databáze: | OpenAIRE |
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