HELICOBACTER PYLORI INFECTION AMONG KINDERGARTEN CHILDREN IN MATARAM
Autor: | Didacus Sumarsidi, Stephanus Gunawan, Luh Gde Sri Astiti, Suwignyo Sumoharjo, Rina Rosalina, Zainul Muttaqin |
---|---|
Rok vydání: | 2000 |
Předmět: |
medicine.medical_specialty
Helicobacter pylori infection Hepatology biology business.industry media_common.quotation_subject Significant difference Gastroenterology Helicobacter pylori biology.organism_classification Antigen Hygiene Internal medicine Immunology Chi-square test biology.protein Medicine Antibody business Helicobacter pylori culture media_common |
Zdroj: | Journal of Gastroenterology and Hepatology. 15:H1-H2 |
ISSN: | 1440-1746 0815-9319 |
DOI: | 10.1046/j.1440-1746.2000.000a4.x |
Popis: | Objective The prevalence of Helicobacter pylori infection in developing countries is relatively high due to the improper hygiene and sanitation. In the developing countries the infection started in very early age. The prevalence of Anti-Helicobacter pylori among blood donor in Mataram is among the highest in Indonesia. The objective of this study is to measure antibody to Helicobacter pylori in Kindergarten children using Passive Hemaglutination (PHA) method that had been proven to have a high sensitivity and specificity compared to the results of Helicobacter pylori culture. Material and Method The venous blood were drawn from 441 kindergarten children aged 3 - 7 years old, consist of 207 female and 234 male. The sera was assayed for antibody to Helicobacter pylori using Passive Hemaglutination Method (PHA) consist of glutaraldehyde fixed type O human erythrocyte coated with purified outer antigen of Helicobacter pylori. Result Anti-Helicobacter pylori was positive using PHA in 216 children (49.4%), consist of 111 female (53.5%) and 107 male (45.7%). Statistic analysis shows no statistically significant difference in Anti-Helicobacter pylori prevalence between male and female (chi square p>0.05). Children from relatively high social economic level showed lower Anti-Helicobacter pylori (41.01%) compared with children from lower socioeconomic level (55,13%) and the difference is statistically significant (chi square p < 0.05). Conclusion In Mataram Helicobacter pylori infection were acquired at very early age so that in preschool age almost 50% of the children have been infected with Helicobacter pylori. The prevalence of Helicobacter pylori infection is higher in the low socioeconomic compared to high socioeconomic level. |
Databáze: | OpenAIRE |
Externí odkaz: |