Twenty-Year Outcome of Aortic Valve Replacement With St. Jude Medical Mechanical Valves in Japanese Patients
| Autor: | Tomonobu Abe, Yohei Okawa, Shuichi Okonogi, Tatsuo Kaneko, Shigeki Yanagi, Akihiko Usui, Nobushige Tamura, Kenji Minakata, Ryuzo Sakata, Shiro Tanaka |
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| Rok vydání: | 2015 |
| Předmět: |
Aortic valve
medicine.medical_specialty business.industry Retrospective cohort study Mean age General Medicine medicine.disease Mechanical valve Surgery medicine.anatomical_structure Aortic prosthesis Aortic valve replacement Internal medicine Cardiology Medicine In patient Cardiology and Cardiovascular Medicine business Major bleeding |
| Zdroj: | Circulation Journal. 79:2380-2388 |
| ISSN: | 1347-4820 1346-9843 |
| DOI: | 10.1253/circj.cj-15-0793 |
| Popis: | Background Bioprostheses have become increasingly popular for aortic valve replacement (AVR) in recent years, but mechanical valves are still the standard choice, especially for younger patients. The aim of this study was to assess the very long-term outcomes in Japanese patients who underwent AVR with St. Jude Medical (SJM) mechanical valves. Methods and results From 1991 to 2001, a total of 816 patients underwent AVR with SJM mechanical valves in 5 hospitals. Of these, 801 patients (mean age, 58.3±11.7 years) were analyzed in this study. There were 24 in-hospital deaths (3.0%). Mean follow-up duration was 11.6±6.7 years and the 10-year follow-up rate was 84.1%. Freedom from valve-related death at 5, 10, 15, and 20 years was 96.2%, 92.7%, 88.8%, and 86.6%, respectively. The linearized ratio of major bleeding events and thromboembolic events was 1.1% per patient-year and 1.0% per patient-year, respectively. Freedom from reoperation for the aortic prosthesis was 98.0% and 94.8% at 10 and 20 years, respectively. Conclusions The SJM mechanical valve provided excellent long-term freedom from valve-related death and reoperation in patients undergoing AVR. Therefore, this valve should be recommended to younger patients who wish to avoid reoperation. |
| Databáze: | OpenAIRE |
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