Heroin-Induced Toxic Leukoencephalopathy From 'Chasing the Dragon' and the Proposed Synergistic Effect of Amantadine and Antioxidants in Its Treatment

Autor:	Alexis Cohen-Oram, Shixie Jiang, Heather Burke
Rok vydání:	2021
Předmět:	Aluminum foil business.industry Amantadine Chasing the dragon Pharmacology medicine.disease Heroin Leukoencephalopathy Toxic leukoencephalopathy Psychiatry and Mental health Clinical Psychology Heroin dependence medicine business Cognitive impairment medicine.drug
Zdroj:	Journal of the Academy of Consultation-Liaison Psychiatry. 62:353-356
ISSN:	2667-2960
Popis:	Background “Chasing the dragon” is a method of heating heroin in aluminum foil and inhaling its fumes. This method of use comes with the risk of toxic leukoencephalopathy, a form of white matter disease that can lead to permanent cognitive impairment. Objective This report presents a patient with heroin-induced toxic leukoencephalopathy who showed substantial clinical improvement after trial of amantadine and antioxidant therapy. Conclusion This report highlights the presentation of heroin-induced leukoencephalopathy, a discussion of its management, and the potential synergistic effect of amantadine and antioxidant therapy.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c48fde19e02a8ef36889f9909ae2c5c0 https://doi.org/10.1016/j.jaclp.2020.12.007 Zobrazit plný text záznamu Full Text from ScienceDirect