A clinical and microbiological profile of urinary tract infection in patients with chronic kidney diseases
| Autor: | Siddharth Pugalendhi, R Hemachandar, S. Lokesh, Tarun Kumar Dutta |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Carbapenem business.industry Antibiotic sensitivity Urinary system 030106 microbiology urologic and male genital diseases medicine.disease Meropenem female genital diseases and pregnancy complications 03 medical and health sciences 0302 clinical medicine Internal medicine Inclusion and exclusion criteria medicine Colistin 030212 general & internal medicine business Empiric therapy Kidney disease medicine.drug |
| Zdroj: | International Journal of Advances in Medicine. 6:911 |
| ISSN: | 2349-3933 2349-3925 |
| DOI: | 10.18203/2349-3933.ijam20192263 |
| Popis: | Background: Urinary tract infections (UTIs) are a major public health problem in terms of morbidity and financial cost in CKD patients in India. The resistance pattern of community acquired uropathogens in CKD patients has not been extensively studied. Thus, knowledge of local antimicrobial susceptibility patterns of common uropathogens is essential for prudent empiric therapy of community acquired UTIs. Methods: It is a cross sectional study conducted in a tertiary care hospital involving 65 chronic kidney disease patients with UTI who attended general medicine OPD and those admitted in wards after fulfilling the inclusion and exclusion criteria, after obtaining written informed consent. Blood sample and urine samples were collected from these patients and sent for blood analysis, urine analysis and urine culture and sensitivity. Results: Among 65 CKD participants with UTI who were studied, E. coli (47.7%) and K. pneumoniae (15.4%) were the most common isolates which were sensitive in order of colistin, polymyxin B, meropenem (carbapenem) and less sensitive to other commonly used antibiotics. Conclusions: The main purpose of this study was to find the various common local uropathogens in CKD patients and their antibiotic profile which will help in formulating antibiotic therapies. As previously stated, there are very few studies regarding profile and management of UTI in CKD patients. Hence this study can throw some light into this area. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|