Efficiency of the endoscopic correction of high-grade vesicoureteral reflux in children

Autor: E. Yu. Dyakonova, F. O. Turov, Sergey N. Zorkin, D.S. Shakhnovsky, A. T. Galuzinskaya
Rok vydání: 2020
Předmět:
Zdroj: Russian Journal of Pediatric Surgery. 24:292-296
ISSN: 2412-0677
1560-9510
Popis: Introduction. The endoscopic correction of vesicoureteral reflux in children has become a basic treatment technique. Its effectiveness in the low-grade reflux is high. High-grade refluxes are an indication for antireflux reconstructive plastic surgery. The article analyzes outomes of endoscopic treatment of patients with high-grade retrograde urine reflux. Material and methods. A total number of 307 patients (409 ureters) with IV-V grade of vesicoureteral reflux were treated. 156 girls and 151 boys, aged 4 months - 12 years, had the endoscopic correction with Dextranomer and Copolymer of Polyacrylic Polyvinyl Alcohol (PPC). The renal parenchyma damage was assessed with DMSA scan; urinary tract infection - with clinical and laboratory findings (febrile temperature and bacteriuria). Outcomes of treatment were evaluated with micurating cystography performed six months later. It revealed either no reflux or its lower grade - grade one. Average follow-up period was 5. 5 years. Results. The effectiveness of endoscopic correction of vesicoureteral reflux after the first injection was 68.7%. The second injection was effective in 48.9%. Febrile urinary tract infection after the treatment went down up to 6.2%. Marked bacteriuria remained high - 55.3%. Renal parenchyma structural and functional damage was noted in 38.9% of older children; mild and moderate degrees of damage prevailed (45.6% and 40.8%, respectively). Conclusion. The endoscopic correction of high-grade vesicoureteral reflux is recommended as the first line treatment for retrograde urine reflux. This technique is highly effective and minimally invasive.
Databáze: OpenAIRE