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Aim. To analyze the efficiency of the use of inosit in the treatment of polycystic ovary syndrome (PCOS) in women of reproductive age.Materials and methods. The prospective study included 80 patients aged 21 to 35 years with a diagnosis of PCOS. The main group consisted of 45 women who were prescribed inosit and lifestyle modification to correct symptoms of PCOS. The control group consisted of 35 women for whom was recommended only lifestyle modification. The condition of the patients was assessed at the beginning of therapy, after 3 and 6 months.Results. During therapy, the patients of the main group showed a statistically significant effect of inosit on metabolic status: a decrease in fasting glucose and insulin levels, body mass index; hormonal status: a decrease in the level of androstenedione, testosterone, LH, normalization of the LH/FSH, a decrease in the clinical manifestations of hyperandrogenism; restored menstrual cycle with ovulationConclusions. The use of inosit along with a balanced diet and physical activity is an effective means for correcting clinical manifestations and improving the quality of life of women with PCOS. |
