SRSF5 regulates alternative splicing of DMTF1 pre-mRNA through modulating SF1 binding

Autor: Hao Wang, Dangdang Li, Jinming Shi, Daniel B. Stovall, Yige Qi, Guangchao Sui, Jialiang Li, Ke Shi, Yao Lu, Guangyue Li
Rok vydání: 2021
Předmět:
Zdroj: RNA Biology. 18:318-336
ISSN: 1555-8584
1547-6286
DOI: 10.1080/15476286.2021.1947644
Popis: Among the three DMTF1 splicing isoforms, DMTF1α acts as a tumour suppressor through promoting p14ARF expression, while DMTF1β exhibits an oncogenic role likely through antagonizing DMTF1α. However,...
Databáze: OpenAIRE