Hematologic and vitamin status of african american women and their relationships to pregnancy outcome
| Autor: | Enid M. Knight, George H. Nolan, Bernice G. Spurlock, Edwards Ch, Allan A. Johnson, William L. West, Sidney Jones, U. Jean Oyemade, Haziel Laryea, O. Jackson Cole, Duane Bonds, Malcolm G. Manning, Lennox Westhey |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Vitamin
education.field_of_study medicine.medical_specialty Pregnancy Nutrition and Dietetics medicine.diagnostic_test business.industry Endocrinology Diabetes and Metabolism Population Gestational age Physiology Hematocrit medicine.disease B vitamins chemistry.chemical_compound Endocrinology chemistry Internal medicine Gestation Medicine Vitamin B12 business education |
| Zdroj: | Nutrition Research. 11:1357-1375 |
| ISSN: | 0271-5317 |
| DOI: | 10.1016/s0271-5317(05)80469-5 |
| Popis: | A prospective observational study was conducted to investigate the effects of nutrition and related factors on the outcome of pregnancy in nulliparous African American women 16–35 years of age. Blood samples from a subset of these subjects were taken during the first (1st), second (2nd) and third (3rd) trimesters of pregnancy and at delivery. Cord blood samples were also collected at delivery. Levels of selected biochemical variables including serum ferritin, vitamin B 12 and folate as well as whole blood folate, and selected hematologic indices were determined and correlated with pregnancy outcome variables. During the second trimester of pregnancy, values for hematocrit and hemoglobin were less than 30% and 11 g/dL, respectively, in 16% and 30% of the participants, respectively. Serum and whole blood (WB) folate increased sequentially during pregnancy. Cord concentrations of serum folate were significantly higher than maternal concentrations at delivery (P 2 =0.21), while gestational age was inversely correlated with 3rd trimester vitamin B 12 (R 2 =0.34). These data suggest that vitamin B 12 and folate play an important role in the outcome of pregnancy in this population. |
| Databáze: | OpenAIRE |
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