Properties of the Cell Surface Fc-Receptor Induced by Herpes Simplex Virus

Autor:	Yoshiko Nakamura, Jose Costa, Tommie Sue Tralka, Carole L. Yee, Alan S. Rabson
Rok vydání:	1978
Předmět:	Immunology Immunology and Allergy
Zdroj:	The Journal of Immunology. 121:1128-1131
ISSN:	1550-6606 0022-1767
DOI:	10.4049/jimmunol.121.3.1128
Popis:	Detection of peroxidase-antiperoxidase soluble complexes (PAP) bound to the surface of herpes simplex virus-infected cells has been used to demonstrate virusinduced Fc receptors and to study their distribution. The PAP method is more sensitive than hemadsorption with immunoglobulin-coated sheep red blood cells, and can be used to study localization by light and electron microscopy. Our results indicate that capping takes place after the receptor is engaged by antigen-antibody complexes and that at least a portion of the bound ligand is internalized.
Databáze:	OpenAIRE
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