Larvicidal effects of a flabelliferin saponin from palmyrah flour on dengue mosquito Aedes sp
| Autor: | E.R. Jansz, A. A. Punya Keerthi, Sagarika Ekanayaka |
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| Rok vydání: | 2007 |
| Předmět: | |
| Zdroj: | Journal of the National Science Foundation of Sri Lanka. 35:133 |
| ISSN: | 2362-0161 1391-4588 |
| DOI: | 10.4038/jnsfsr.v35i2.3678 |
| Popis: | Abastract: The ethanolic extractives of palmyrah (Borassus flabellifer L.) flour were toxic to the dengue mosquito {Aedes albopictus and Aedes aegypti) larvae with LD50 value of 60 mg/L to 76 mg/L depending on larval molting stage. A single compound was isolated from the ethanolic extractives by medium pressure liquid chromatography, by bioassay directed fractionation at a fold purification of >1000. This compound had the chemical characteristics of a saponin belonging to the group flabelliferin. It had a molecular weight (MW) of 868 and confirmed 1 Glc and 2 Rha by mass spectroscopy. The pure compound was found to be lethal to dengue mosquitoes. The lethality is due to the above saponin causing a physical barrier visible only by froth on shaking. The saponin can also lower the surface tension of water surface. Thus, the Aedes mosquito larvae cannot hang on to the water surface to expose their breathing siphons into the air. Culex quinquefasciatus, with long breathing siphons is not effected. The application of these compounds to free aquatic environment is limited as the compounds showed toxicity to a lung breathers Micoglanis iheringis (anntena catfish) and also for a gill breather Poecilia reticulata (guppy). However, it could be used as a remedy in controlling dengue mosquito larvae in vases, containers and other discard household utensils in which this dengue mosquito often breed. |
| Databáze: | OpenAIRE |
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