A novel and simple method for the silylation of alcohols in DMSO–hexane without a catalyst

Autor:	Masaya Matsuzaki, Tsutomu Watahiki, Takeshi Oriyama
Rok vydání:	2003
Předmět:	Reaction conditions Silylation organic chemicals Pollution Chloride Catalysis Cyclopropane Hexane chemistry.chemical_compound chemistry medicine Environmental Chemistry Moiety Organic chemistry Tetrahydrofuran medicine.drug
Zdroj:	Green Chemistry. 5:82-84
ISSN:	1463-9270 1463-9262
Popis:	Reaction of alcohols with tert-butyldimethylsilyl chloride in DMSO–hexane provides the corresponding tert-butyldimethylsilyl ethers in high yields under mild reaction conditions. This convenient reaction proceeds very smoothly at room temperature without a catalyst. Additionally, alcohols having an allylic alcohol, cyclopropane, and tetrahydrofuran moiety underwent chemoselective silylation to give the TBS ethers in good yields with no undesired reactions.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c3fda66cc9fa3b5455d833ae58dd8fbe https://doi.org/10.1039/b209506h Zobrazit plný text záznamu