Bone Formation of Cultured Osteoblasts in Bone Defect of Radial Shaft of Rabbit

Autor:	Seok Jung Kim, Jae Deog Jang, Seung Koo Lee, Cheong Ho Chang, Won Jong Bahk, Yong In, Hyung Moon Yoon
Rok vydání:	2005
Předmět:	medicine.medical_specialty Bone union business.industry medicine.medical_treatment Rabbit (nuclear engineering) Osteoblast Bone healing Bone grafting Bone defect Surgery medicine.anatomical_structure medicine Bone formation Anterior approach business
Zdroj:	Journal of the Korean Orthopaedic Association. 40:76
ISSN:	2005-8918 1226-2102
DOI:	10.4055/jkoa.2005.40.1.76
Popis:	Purpose: To evaluate the osteogenic potential of an autologous cultured osteoblast transplant to the bone defects. Materials and Methods: Radial bone defects over 15 mm were made in 20 New Zealand white rabbits using the anterior approach. There were 10 rabbits in the control group, which underwent an iliac bone graft to the preformed bone defect 3 weeks from the initial operation. There were 10 rabbits in the experimental group that underwent an autologous cultured osteoblasts injection. After 9 weeks, both groups were compared radiologically and histologically. Results: The osteogenesis in both groups were progressed similarly and there was no difference in terms of the amount of bone formation and the duration of the bone union. Conclusion: An autologous cultured osteoblast transplant to the bone defect produces bone efficiently. In addition, it can be applied to a wide field, which requires a bone grafting operation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c3a4bde608135b76f5e1cf6f4987924f https://doi.org/10.4055/jkoa.2005.40.1.76 Zobrazit plný text záznamu