Glucose Abnormalities and Inappropriate Weight Gain Predict Negative Pregnancy Outcomes After Gastric Bypass Surgery
| Autor: | M. Coustols, P Guerby, Olivier Parant, G. Tuyeras, Patrick Ritz, Hélène Hanaire, B. Guyard-Boileau, Monelle Bertrand, H Gohier |
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| Rok vydání: | 2021 |
| Předmět: |
Pregnancy
medicine.medical_specialty Nutrition and Dietetics business.industry Obstetrics Gastric bypass surgery Endocrinology Diabetes and Metabolism medicine.medical_treatment Gestational age 030209 endocrinology & metabolism Retrospective cohort study medicine.disease medicine.disease_cause Gestational diabetes 03 medical and health sciences 0302 clinical medicine medicine Small for gestational age 030211 gastroenterology & hepatology Surgery Caesarean section medicine.symptom business Weight gain |
| Zdroj: | Obesity Surgery. 31:3123-3129 |
| ISSN: | 1708-0428 0960-8923 |
| Popis: | Pregnancy after gastric bypass (RYGB) surgery remains at high risk for gestational diabetes mellitus, prematurity, and small for gestational age infants (SGA). Our objective was to describe the interstitial glucose (IG) profiles and weight changes during such pregnancies, and the association of these factors with adverse pregnancy outcomes. One hundred twenty two pregnancies were analyzed in a monocentric retrospective study. IG profiles were evaluated by continuous glucose monitoring for 4 days. Maternal (hypertension, hospitalizations, and caesarean section) and neonatal outcomes (prematurity, weight for gestational age, hospitalizations, and malformations) were recorded. A logistic stepwise regression model assessed the influence of weight gain and impaired IG on pregnancy outcomes. Pregnancies occurred 33 (SD 21 months) after surgery. 73% of the women had IG abnormalities (55% with an increased % of time >140 mg/dl and 69% with an increased % of time 140 mg/dl and an excessive maternal weight gain. Prematurity was associated with a high % of time |
| Databáze: | OpenAIRE |
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