Studies on the mechanisms of resistance to hypoxia a review

Autor: Z. I. Barbashova
Rok vydání: 1967
Předmět:
Zdroj: International Journal of Biometeorology. 11:243-254
ISSN: 1432-1254
0020-7128
DOI: 10.1007/bf01426648
Popis: The review summarises results of experimental research in Russia.The ultimate response mechanism of the hypoxic stimulus appears to reside in the cell itself and is activated by the direct action of nervous stimulation on the tissues involved and/or various hormonal regulatory systems.The adaptive mechanism in the cell to hypoxia involves a change in the cellular metabolism mediated by various enzymatic alterations. These cellular alterations,according to the principle of negative feedback, readjust the control of the nervous input from the lower and higher regulatory centers to a level corresponding to the changed environmental stimulus. Therefore, a new level in the coordination of the functional systems is established and the organism's general resistance is enhanced to hypoxia, the ultimate stimulus.
Databáze: OpenAIRE